Basic Information

Terpenoid ID TKC067542
Chirality TKC108631
Cell line 0
Protein target 12
DiseaseNCIT 0
ORDO 0
ICD 11

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC067542 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 18356 nM Potency
TKC067542 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 29093 nM Potency
TKC067542 O95398 Rap guanine nucleotide exchange factor 3 RAPGEF3 35481 nM Potency
TKC067542 P84022 Mothers against decapentaplegic homolog 3 SMAD3 12589 nM Potency
TKC067542 Q77YF9 Protein Vpr vpr 63096 nM Potency
TKC067542 O75164 Lysine-specific demethylase 4A KDM4A 35481 nM Potency
TKC067542 Q9UNA4 DNA polymerase iota POLI 25119 nM Potency
TKC067542 O75496 Geminin GMNN 11582 nM Potency
TKC067542 P39748 Flap endonuclease 1 FEN1 50119 nM Potency
TKC067542 Q13148 TAR DNA-binding protein 43 TARDBP 35481 nM Potency
TKC067542 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1 44668 nM Potency
TKC067542 O75356 Ectonucleoside triphosphate diphosphohydrolase 5 ENTPD5 10000 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Liver cancer [ICD-11: 2C12]
O75874 IDHC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O95398 RPGF3_HUMAN Epidermal dysplasias [ICD-11: EK90]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q13148 TADBP_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
Q13148 TADBP_HUMAN Alzheimer disease [ICD-11: 8A20]
Q13526 PIN1_HUMAN Lung cancer [ICD-11: 2C25]
Q13526 PIN1_HUMAN Nasopharyngeal cancer [ICD-11: 2B6B]