Basic Information

Terpenoid ID TKC057132
Chirality TKC148601
Cell line 0
Protein target 4
DiseaseNCIT 0
ORDO 0
ICD 28

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC057132 Raji RAJI; P1-Raji; GM04671 70.0 % Activity C27694 Orphanet_543
TKC057132 PANC-1 Panc-1; PANC.1; Panc 1; PanC1; Panc1; PANC1; Panc-1-P 69.0 uM PC50 C9120

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC057132 Q9NPD5 Solute carrier organic anion transporter family member 1B3 SLCO1B3 91 % Inhibition
TKC057132 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 SLCO1B1 54 % Inhibition
TKC057132 Q07869 Peroxisome proliferator-activated receptor alpha PPARA 12589 nM Potency
TKC057132 P02511 Alpha-crystallin B chain CRYAB 1420 nM EC50
TKC057132 P10613 Lanosterol 14-alpha demethylase ERG11 7400 nM Km
TKC057132 P9WPL4 Steroid C26-monooxygenase cyp142 37 % Activity
TKC057132 Q16850 Lanosterol 14-alpha demethylase CYP51A1 30000 nM Km
TKC057132 Q96W81 14-alpha sterol demethylase cyp51B 3 uM Ks

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q07869 PPARA_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
Q07869 PPARA_HUMAN Hyperlipidemia [ICD-11: 5C80]
Q07869 PPARA_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
Q07869 PPARA_HUMAN Inborn lipid metabolism error [ICD-11: 5C52]
Q07869 PPARA_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
Q07869 PPARA_HUMAN Diabetes mellitus [ICD-11: 5A10]
Q07869 PPARA_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q07869 PPARA_HUMAN Acute diabete complication [ICD-11: 5A2Y]
Q07869 PPARA_HUMAN Dyslipidemia [ICD-11: 5C80-5C81]
Q07869 PPARA_HUMAN Gout [ICD-11: FA25]
Q07869 PPARA_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q07869 PPARA_HUMAN Heart failure [ICD-11: BD10-BD1Z]
Q07869 PPARA_HUMAN Arterial occlusive disease [ICD-11: BD40]
Q07869 PPARA_HUMAN Idiopathic interstitial pneumonitis [ICD-11: CB03]
Q07869 PPARA_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]
Q07869 PPARA_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P10613 CP51_CANAL Aspergillosis [ICD-11: 1F20]
P10613 CP51_CANAL Candidosis [ICD-11: 1F23]
P10613 CP51_CANAL Dermatophytosis [ICD-11: 1F28]
P10613 CP51_CANAL Fungal infection [ICD-11: 1F29-1F2F]
P10613 CP51_CANAL Nail/perionychium infection [ICD-11: EE12]
P10613 CP51_CANAL Non-dermatophyte superficial dermatomycose [ICD-11: 1F2D]
P10613 CP51_CANAL Visual system disease [ICD-11: 9E1Z]
P10613 CP51_CANAL Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P10613 CP51_CANAL Oesophagitis [ICD-11: DA24]
P10613 CP51_CANAL Hyper-lipoproteinaemia [ICD-11: 5C80]
Q16850 CP51A_HUMAN Infectious meningitis [ICD-11: 1D01]
Q16850 CP51A_HUMAN Nail/perionychium infection [ICD-11: EE12]
Q16850 CP51A_HUMAN Onchocerciasis [ICD-11: 1F6A]