Basic Information

Terpenoid ID TKC050432
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 1

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC050432 Vero VERO; VeroCCL81; Vero 81; Vero-81; Verda reno 15000.0 nM IC50
TKC050432 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 20.0 ug.mL-1 IC50 C9154 Orphanet_519
TKC050432 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 23.0 ug.mL-1 IC50 C27677
TKC050432 A549 22.0 ug.mL-1 IC50 C3512
TKC050432 KB KB (HeLa derivative); HeLa-KB; Strain KB 15800.0 nM IC50 C27677
TKC050432 L1210 L 1210; L-1210; Leukemic 1210; Leukemia 1210; Leukemia L1210 16300.0 nM IC50 C21604
TKC050432 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 3620.0 nM GI50 C4910
TKC050432 MCF7 3600.0 nM GI50 C4194
TKC050432 HSC-2 HSC2 50700.0 nM IC50 C4833 Orphanet_502363
TKC050432 SK-MEL-2 SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 3070.0 nM GI50 C3224
TKC050432 UACC-62 UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 1730.0 nM GI50 C3224
TKC050432 COLO 205 Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 2630.0 nM GI50 C4349

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC050432 Q00653 Nuclear factor NF-kappa-B p100 subunit NFKB2 1060 nM IC50
TKC050432 Q07817 Bcl-2-like protein 1 BCL2L1 >100000 nM Ki

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q00653 NFKB2_HUMAN Ulcerative colitis [ICD-11: DD71]
Q07817 B2CL1_HUMAN Mature B-cell leukaemia [ICD-11: 2A82]
Q07817 B2CL1_HUMAN Myeloproliferative neoplasm [ICD-11: 2A20]
Q07817 B2CL1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q07817 B2CL1_HUMAN Lung cancer [ICD-11: 2C25]
Q07817 B2CL1_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
Q07817 B2CL1_HUMAN Mature T-cell lymphoma [ICD-11: 2A90]