Basic Information

Terpenoid ID TKC048310
Chirality TKC151720
Cell line 0
Protein target 2
DiseaseNCIT 0
ORDO 0
ICD 7

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC048310 SF-188 SF-188; SF 188 17.0 % Activity C3058 Orphanet_360
TKC048310 U-87 MG 51.0 % Activity C3058 Orphanet_360
TKC048310 HUVEC HUV-EC-C; HUVEC 2.0 ug.mL-1 EC50
TKC048310 MCF7 6620.0 nM IC50 C4194
TKC048310 HepG2 39420.0 nM IC50 C3728 Orphanet_449
TKC048310 DU-145 DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 60410.0 nM IC50 C4863
TKC048310 COLO 205 Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 49160.0 nM IC50 C4349
TKC048310 A549 99890.0 nM IC50 C3512
TKC048310 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 15530.0 nM IC50 C9154 Orphanet_519
TKC048310 LLC-PK1 LLC-PK(1); LLC-PK-1; LLC PK-1; LLc-PK1; LLC PK1; LLCPK1; Lilly Laboratories Culture-Porcine Kidney 1 36700.0 nM IC50
TKC048310 MDA-MB-231 MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 5900.0 nM IC50 C5214

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC048310 P18031 Tyrosine-protein phosphatase non-receptor type 1 PTPN1 23600 nM IC50
TKC048310 P0DTD1 Replicase polyprotein 1ab rep 0 % Inhibition
TKC048310 O70536 Sterol O-acyltransferase 1 Soat1 30000 nM IC50
TKC048310 Q02769 Squalene synthase Fdft1 20 % Inhibition

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P18031 PTN1_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P18031 PTN1_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P18031 PTN1_HUMAN Obesity [ICD-11: 5B80-5B81]
P18031 PTN1_HUMAN Ophthalmic devices/implants/grafts injury [ICD-11: PK97]
P18031 PTN1_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P18031 PTN1_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]