Basic Information

Terpenoid ID TKC037522
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 7

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC037522 MOLM-13 MOLM13; Molm13; Molm 13 13.0 uM LD50 C9154 Orphanet_519
TKC037522 MV4-11 MV-4-11; MV-4:11; MV4:11; MV 4;11; MV4;11; MV411; MV(4;11); MV4II 5.0 uM LD50 C9163 Orphanet_514
TKC037522 KG-1 KG1 19.0 uM LD50 C9154 Orphanet_519
TKC037522 Kasumi 1 KASUMI-1; Kasumi 1; KASUMI1; Kasumi1 13.0 uM LD50 C9381 Orphanet_98834
TKC037522 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 14.0 uM LD50 C9154 Orphanet_519
TKC037522 U-937 U937; U 937 19.0 uM LD50 C8263 Orphanet_514
TKC037522 TUR TPA-U937-resistant 12.0 uM LD50 C8263 Orphanet_514
TKC037522 THP-1 THP1; THP 1; THPI; THP-1(ATCC); THP-1-O; O-THP-1; Tohoku Hospital Pediatrics-1 17.0 uM LD50 C9163 Orphanet_514
TKC037522 MCF7 5000.0 nM IC50 C4194
TKC037522 HeLa S3 HeLa s3; HeLa-S3; HELA-S3; HeLa/S3; HeLa.S3; HeLa S 3; HeLa S-3; HeLaS3; HeLa, S3 clone; S3-HeLa; S3 HeLa 10000.0 nM IC50 C27677
TKC037522 KB KB (HeLa derivative); HeLa-KB; Strain KB 5300.0 nM IC50 C27677
TKC037522 Leukemia cells 9.0 uM LD50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC037522 Q00653 Nuclear factor NF-kappa-B p100 subunit NFKB2 50 uM IC100
TKC037522 Q04206 Transcription factor p65 RELA 50 uM IC100
TKC037522 P11511 Aromatase CYP19A1 15 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q00653 NFKB2_HUMAN Ulcerative colitis [ICD-11: DD71]
P11511 CP19A_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P11511 CP19A_HUMAN Cushing syndrome [ICD-11: 5A70]
P11511 CP19A_HUMAN Oesophagitis [ICD-11: DA24]
P11511 CP19A_HUMAN Endometriosis [ICD-11: GA10]
P11511 CP19A_HUMAN Neuropathy [ICD-11: 8C0Z]
P11511 CP19A_HUMAN Bladder cancer [ICD-11: 2C94]
P11511 CP19A_HUMAN Prostate disease [ICD-11: GA91]