Basic Information

Terpenoid ID TKC033765
Cell line 1
Protein target 5
DiseaseNCIT 1
ORDO 0
ICD 19

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC033765 RBL-2H3 RBL2H3; RBL 2H3; RBL.2H3 2.0 % Inhibition C60428
TKC033765 A549 58.0 ug ml-1 ID50 C3512
TKC033765 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 4.0 ug ml-1 ID50 C9154 Orphanet_519

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC033765 Q9NPD5 Solute carrier organic anion transporter family member 1B3 SLCO1B3 -3 % Inhibition
TKC033765 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 SLCO1B1 26 % Inhibition
TKC033765 O94956 Solute carrier organic anion transporter family member 2B1 SLCO2B1 -72 % Inhibition
TKC033765 Q8NER1 Transient receptor potential cation channel subfamily V member 1 TRPV1 176 % Activity
TKC033765 Q96D31 Calcium release-activated calcium channel protein 1 ORAI1 53 % Activity

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q8NER1 TRPV1_HUMAN Visual system disease [ICD-11: 9E1Z]
Q8NER1 TRPV1_HUMAN General pain disorder [ICD-11: 8E43]
Q8NER1 TRPV1_HUMAN Knee osteoarthritis [ICD-11: FA01]
Q8NER1 TRPV1_HUMAN Lower limb mononeuropathy [ICD-11: 8C11]
Q8NER1 TRPV1_HUMAN Pain [ICD-11: MG30-MG3Z]
Q8NER1 TRPV1_HUMAN Atopic eczema [ICD-11: EA80]
Q8NER1 TRPV1_HUMAN Chronic pain [ICD-11: MG30]
Q8NER1 TRPV1_HUMAN Functional bladder disorder [ICD-11: GC50]
Q8NER1 TRPV1_HUMAN Migraine [ICD-11: 8A80]
Q8NER1 TRPV1_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
Q8NER1 TRPV1_HUMAN Rheumatoid arthritis [ICD-11: FA20]
Q8NER1 TRPV1_HUMAN Asthma [ICD-11: CA23]
Q8NER1 TRPV1_HUMAN Acute/chronic pain [ICD-11: MG30-MG31]
Q8NER1 TRPV1_HUMAN Esophagus sensitivity [ICD-11: DA2Y-DA2Z]
Q8NER1 TRPV1_HUMAN Gastro-oesophageal reflux disease [ICD-11: DA22]
Q8NER1 TRPV1_HUMAN Neuropathy [ICD-11: 8C0Z]
Q8NER1 TRPV1_HUMAN Zoster [ICD-11: 1E91]
Q8NER1 TRPV1_HUMAN Cough [ICD-11: MD12]
Q96D31 CRCM1_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]