Basic Information

Terpenoid ID TKC032440
Cell line 0
Protein target 2
DiseaseNCIT 0
ORDO 0
ICD 28

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC032440 L5178Y L5178Y; LY 2.0 ug.mL-1 EC50 C21604
TKC032440 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 8.0 ug.mL-1 EC50 C27677

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC032440 P25101 Endothelin-1 receptor EDNRA 135000 nM IC50
TKC032440 P24530 Endothelin receptor type B EDNRB 50000 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P25101 EDNRA_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P25101 EDNRA_HUMAN Pulmonary hypertension [ICD-11: BB01]
P25101 EDNRA_HUMAN Chronic kidney disease [ICD-11: GB61]
P25101 EDNRA_HUMAN Coronary vasospastic disease [ICD-11: BA85]
P25101 EDNRA_HUMAN Hypertension [ICD-11: BA00-BA04]
P25101 EDNRA_HUMAN Hypotension [ICD-11: BA20-BA21]
P25101 EDNRA_HUMAN Myocardial infarction [ICD-11: BA41-BA43]
P25101 EDNRA_HUMAN Prostate cancer [ICD-11: 2C82]
P25101 EDNRA_HUMAN Retinal vascular occlusion [ICD-11: 9B74]
P25101 EDNRA_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
P25101 EDNRA_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
P25101 EDNRA_HUMAN Depression [ICD-11: 6A70-6A7Z]
P25101 EDNRA_HUMAN Increased intracranial pressure [ICD-11: 8D60]
P25101 EDNRA_HUMAN Cardiac arrhythmia [ICD-11: BC9Z]
P25101 EDNRA_HUMAN Cerebrovascular disease [ICD-11: 8B22-8B2Z]
P25101 EDNRA_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P25101 EDNRA_HUMAN Unspecific body region injury [ICD-11: ND56]
P25101 EDNRA_HUMAN Heart disease [ICD-11: BA41-BA42]
P25101 EDNRA_HUMAN Preterm labour/delivery [ICD-11: JB00]
P24530 EDNRB_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P24530 EDNRB_HUMAN Pulmonary hypertension [ICD-11: BB01]
P24530 EDNRB_HUMAN Encephalopathy [ICD-11: 8E47]
P24530 EDNRB_HUMAN Hypertension [ICD-11: BA00-BA04]
P24530 EDNRB_HUMAN Kidney failure [ICD-11: GB60-GB6Z]
P24530 EDNRB_HUMAN Myasthenia gravis [ICD-11: 8C6Y]
P24530 EDNRB_HUMAN Neuromyelitis optica [ICD-11: 8A43]
P24530 EDNRB_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P24530 EDNRB_HUMAN Cardiac arrhythmia [ICD-11: BC9Z]