Basic Information

Terpenoid ID TKC027341
Cell line 0
Protein target 4
DiseaseNCIT 0
ORDO 0
ICD 44

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC027341 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 60000.0 nM IC50 C4910
TKC027341 OVCAR 65000.0 nM IC50 C105555
TKC027341 A549 60000.0 nM IC50 C3512
TKC027341 MCF7 40000.0 nM IC50 C4194
TKC027341 PC-3 PC3; PC.3 40000.0 nM IC50 C4863
TKC027341 HepG2 60000.0 nM IC50 C3728 Orphanet_449
TKC027341 SH-SY5Y SH-Sy5y; SHSY5Y; SHSY-5Y; SK-SH-SY5Y; SY5Y; SH-SY5Y Parental 77000.0 nM IC50 C3270 Orphanet_635
TKC027341 RBL-2H3 RBL2H3; RBL 2H3; RBL.2H3 12300.0 nM IC50 C60428

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC027341 P21554 Cannabinoid receptor 1 CNR1 714 nM Ki
TKC027341 Q6RI86 Transient receptor potential cation channel subfamily A member 1 Trpa1 60 nM EC50
TKC027341 P97612 Fatty-acid amide hydrolase 1 Faah >47 % Emax
TKC027341 Q02083 N-acylethanolamine-hydrolyzing acid amidase NAAA >41 % Emax
TKC027341 Q9Y4D2 Diacylglycerol lipase-alpha DAGLA 100000 nM IC50
TKC027341 P34972 Cannabinoid receptor 2 CNR2 257 nM Ki

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P21554 CNR1_HUMAN Anorexia nervosa [ICD-11: 6B80]
P21554 CNR1_HUMAN Insomnia [ICD-11: 7A00-7A0Z]
P21554 CNR1_HUMAN Nausea/vomiting [ICD-11: MD90]
P21554 CNR1_HUMAN Obesity [ICD-11: 5B80-5B81]
P21554 CNR1_HUMAN Nicotine use disorder [ICD-11: 6C4A]
P21554 CNR1_HUMAN Urinary tract infection [ICD-11: GC08]
P21554 CNR1_HUMAN Cannabis use disorder [ICD-11: 6C41]
P21554 CNR1_HUMAN Chronic kidney disease [ICD-11: GB61]
P21554 CNR1_HUMAN Colorectal cancer [ICD-11: 2B91]
P21554 CNR1_HUMAN Inborn lipid metabolism error [ICD-11: 5C52]
P21554 CNR1_HUMAN Pain [ICD-11: MG30-MG3Z]
P21554 CNR1_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P21554 CNR1_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]
P21554 CNR1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P21554 CNR1_HUMAN General pain disorder [ICD-11: 8E43]
P21554 CNR1_HUMAN Low bone mass disorder [ICD-11: FB83]
P21554 CNR1_HUMAN Prostate cancer [ICD-11: 2C82]
P21554 CNR1_HUMAN Ischemia [ICD-11: 8B10-8B11]
P21554 CNR1_HUMAN Psychotic disorder [ICD-11: 6A20-6A25]
P21554 CNR1_HUMAN Zoster [ICD-11: 1E91]
P21554 CNR1_HUMAN Cerebral ischaemia [ICD-11: 8B1Z]
P21554 CNR1_HUMAN Hypertension [ICD-11: BA00-BA04]
P21554 CNR1_HUMAN Schizophrenia [ICD-11: 6A20]
P21554 CNR1_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P21554 CNR1_HUMAN Ovarian cancer [ICD-11: 2C73]
P21554 CNR1_HUMAN Psychoactive substances use disorder [ICD-11: 6C4G]
P34972 CNR2_HUMAN Attention deficit hyperactivity disorder [ICD-11: 6A05]
P34972 CNR2_HUMAN Insomnia [ICD-11: 7A00-7A0Z]
P34972 CNR2_HUMAN Atopic eczema [ICD-11: EA80]
P34972 CNR2_HUMAN Crohn disease [ICD-11: DD70]
P34972 CNR2_HUMAN General pain disorder [ICD-11: 8E43]
P34972 CNR2_HUMAN Inborn lipid metabolism error [ICD-11: 5C52]
P34972 CNR2_HUMAN Pain [ICD-11: MG30-MG3Z]
P34972 CNR2_HUMAN Endometriosis [ICD-11: GA10]
P34972 CNR2_HUMAN Low bone mass disorder [ICD-11: FB83]
P34972 CNR2_HUMAN Prostate cancer [ICD-11: 2C82]
P34972 CNR2_HUMAN Transplant rejection [ICD-11: NE84]
P34972 CNR2_HUMAN Ischemia [ICD-11: 8B10-8B11]
P34972 CNR2_HUMAN Cerebral ischaemia [ICD-11: 8B1Z]
P34972 CNR2_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P34972 CNR2_HUMAN Immune system disease [ICD-11: 4A01-4B41]
P34972 CNR2_HUMAN Indeterminate colitis [ICD-11: DD72]
P34972 CNR2_HUMAN Ovarian cancer [ICD-11: 2C73]
P34972 CNR2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]