Basic Information

Terpenoid ID TKC026600
Cell line 0
Protein target 4
DiseaseNCIT 0
ORDO 0
ICD 11

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC026600 A2780 A-2780; 2780; A2780S; A2780par 10900.0 nM IC50 C7979 Orphanet_454723
TKC026600 SF-268 SF-268; SF.268; SF 268 2700.0 nM GI50 C60781 Orphanet_94
TKC026600 MCF7 8300.0 nM IC50 C4194
TKC026600 NCI-H460 NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 1800.0 nM GI50 C4450
TKC026600 HT-29 HT 29; HT29 5400.0 nM GI50 C4349
TKC026600 CHO-K1 CHO K1; CHOK1; CHO cell clone K1; GM15452 2000.0 nM GI50
TKC026600 T47D 56.0 % GI C4194
TKC026600 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 7600.0 nM IC50 C27677
TKC026600 WI-38 Wi-38; WI 38; WI38; Wistar Institute-38; AG06814E; AG06814G; AG06814H; AG06814-J; AG06814J; AG06814-M; AG06814-N 9700.0 nM IC50
TKC026600 M14 M14-MEL; UCLA-SO-M14; UCLA SO M14; UCLA-SO-14; UCLASO-M14; Melanoma 14; M-14 1811.0 nM GI50 C3802
TKC026600 NCI-H522 NCI.H522; H522; H-522; NCI-522; NCI522; NCIH522 6823.0 nM GI50 C3512
TKC026600 SN12C SN-12C 10520.0 nM GI50 C9385 Orphanet_217071
TKC026600 NCI-H23 NCI.H23; NCI H23; H-23; H23; NCIH23 3048.0 nM GI50 C3512
TKC026600 ACHN 4064.0 nM GI50 C6975 Orphanet_319298
TKC026600 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 2399.0 nM GI50 C9154 Orphanet_519
TKC026600 SF-539 SF-539; SF-539 BT; SF.539; SF 539 2793.0 nM GI50 C3796 Orphanet_251576
TKC026600 Malme-3M MALME-3M; MALME 3M; Malme-3 M; MALME.3M; Malme3M; MALME3M; Malme-3 Monolayer 2904.0 nM GI50 C3224
TKC026600 SK-MEL-5 SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel 2421.0 nM GI50 C3510
TKC026600 K562 K562; K.562; K 562; KO; GM05372; GM05372E 4074.0 nM GI50 C9110 Orphanet_521
TKC026600 OVCAR-3 Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 3532.0 nM GI50 C105555
TKC026600 A498 A498 6266.0 nM GI50 C9385 Orphanet_217071
TKC026600 U-251 U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) 4064.0 nM GI50 C60781 Orphanet_94
TKC026600 OVCAR-8 OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 4406.0 nM GI50 C105555
TKC026600 TK-10 TK.10; TK 10; TK10 7161.0 nM GI50 C4033 Orphanet_319276
TKC026600 SW-620 SW-620; SW 620; SW.620 3013.0 nM GI50 C4349
TKC026600 M19-MEL M-19; M19 1807.0 nM GI50 C3802
TKC026600 KM12 KM-12; KM.12 2723.0 nM GI50 C4910
TKC026600 XF498 XF-498; XF498 16672.0 nM GI50 C3058 Orphanet_360
TKC026600 NCI-H322M NCI.H322M; H322M; H-322M; H-322m 3556.0 nM GI50 C2923
TKC026600 RPMI-8226 RPMI 8226; RPMI.8226; RPMI8226; RPMI no. 8226; RPMI no 8226; RPMI #8226; 8226; RPMI 8226/S; RPMI-8226S; RPMI8226/S; 8226/S; Roswell Park Memorial Institute 8226; GM02132; GM2132; GM 2132; GM02132C; Simpson 2742.0 nM GI50 C3242 Orphanet_29073
TKC026600 OVCAR-4 OVCAR 4; NIH:OVCAR-4; NIH:OVCAR4; OVCAR.4; OVCAR4; Ovcar4 5649.0 nM GI50 C105555
TKC026600 LOX IMVI LOX/IMVI; LOX IMVI; LOXIM-VI; LOXIMVI; LOX 4966.0 nM GI50 C3802
TKC026600 SK-MEL-2 SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 2449.0 nM GI50 C3224
TKC026600 A549 2858.0 nM GI50 C3512
TKC026600 KM-20L2 KM-20L2; KM 20L2; KM 2012 4236.0 nM GI50 C4349
TKC026600 SNB-75 SNB.75; SNB75; Surgical Neurology Branch-75 3945.0 nM GI50 C3058 Orphanet_360
TKC026600 HCC 2998 HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 7889.0 nM GI50 C4349
TKC026600 HCT-15 HCT-15; HCT.15; HCT15 2710.0 nM GI50 C4349
TKC026600 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 3707.0 nM GI50 C4910
TKC026600 SF-268 SF-268; SF.268; SF 268 4305.0 nM GI50 C60781 Orphanet_94
TKC026600 EKVX 6281.0 nM GI50 C3512
TKC026600 LXFL 529 LXFL-529L; LXFL529L; LXF 529 L; LXFL-529; LXFL 529; LXFL529; LXF 529 6039.0 nM GI50 C2926
TKC026600 DMS-114 DMS-114; DMS114; Darmouth Medical School 114 1991.0 nM GI50 C4917 Orphanet_70573
TKC026600 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 12560.0 nM GI50 C7978
TKC026600 UACC-62 UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 2223.0 nM GI50 C3224
TKC026600 NCI-H460 NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 2799.0 nM GI50 C4450
TKC026600 CAKI-1 CAL 1; Centre Antoine Lacassagne-1 3622.0 nM GI50 C3224
TKC026600 IGROV-1 Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P 3221.0 nM GI50 C7979 Orphanet_454723
TKC026600 SF-295 SF-295; SF.295; SF 295 2506.0 nM GI50 C3058 Orphanet_360
TKC026600 RXF 631 RXF-631L; RXF631L; RXF 631; RXF-631; RXF631 9616.0 nM GI50 C9385 Orphanet_217071
TKC026600 786-0 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT 2642.0 nM GI50 C9385 Orphanet_217071
TKC026600 DLD-1 DLD 1; DLD1; CoCL3 7178.0 nM GI50 C4349
TKC026600 UACC-257 UACC 257; UACC.257; UACC257; University of Arizona Cell Culture-257 3304.0 nM GI50 C3224
TKC026600 CCRF-CEM CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C 2355.0 nM GI50 C7953 Orphanet_99861
TKC026600 HT-29 HT 29; HT29 10889.0 nM GI50 C4349
TKC026600 SK-MEL-28 SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 3990.0 nM GI50 C3510
TKC026600 RXF 393 RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL 2729.0 nM GI50 C9385 Orphanet_217071
TKC026600 COLO 205 Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 7345.0 nM GI50 C4349
TKC026600 HOP-18 HOP 18; Hop 18; HOP18; Hop18; Hopkins-18 1702.0 nM GI50 C4450

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC026600 P11597 Cholesteryl ester transfer protein CETP 100000 nM IC50
TKC026600 P06746 DNA polymerase beta POLB 45200 nM IC50
TKC026600 P30305 M-phase inducer phosphatase 2 CDC25B 92000 nM IC50
TKC026600 P23526 Adenosylhomocysteinase AHCY 40000 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P11597 CETP_HUMAN Arterial occlusive disease [ICD-11: BD40]
P11597 CETP_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P11597 CETP_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
P11597 CETP_HUMAN Myocardial infarction [ICD-11: BA41-BA43]
P11597 CETP_HUMAN Inborn lipid metabolism error [ICD-11: 5C52]
P11597 CETP_HUMAN Chronic arterial occlusive disease [ICD-11: BD4Z]
P11597 CETP_HUMAN Dyslipidemia [ICD-11: 5C80-5C81]
P06746 DPOLB_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P30305 MPIP2_HUMAN Lung cancer [ICD-11: 2C25]
P30305 MPIP2_HUMAN Nasopharyngeal cancer [ICD-11: 2B6B]
P30305 MPIP2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]