Basic Information

Terpenoid ID TKC022818
Cell line 0
Protein target 24
DiseaseNCIT 0
ORDO 0
ICD 25

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC022818 HepG2 19953.0 nM Potency C3728 Orphanet_449

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC022818 P04062 Lysosomal acid glucosylceramidase GBA1 14125 nM Potency
TKC022818 P10636 Microtubule-associated protein tau MAPT 22387 nM Potency
TKC022818 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 16360 nM Potency
TKC022818 P43220 Glucagon-like peptide 1 receptor GLP1R 28184 nM Potency
TKC022818 P84022 Mothers against decapentaplegic homolog 3 SMAD3 35481 nM Potency
TKC022818 Q77YF9 Protein Vpr vpr 31623 nM Potency
TKC022818 Q99700 Ataxin-2 ATXN2 39811 nM Potency
TKC022818 O75496 Geminin GMNN 18356 nM Potency
TKC022818 P37840 Alpha-synuclein SNCA 22387 nM Potency
TKC022818 P17405 Sphingomyelin phosphodiesterase SMPD1 25119 nM Potency
TKC022818 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1 19953 nM Potency
TKC022818 Q96QE3 ATPase family AAA domain-containing protein 5 ATAD5 32629 nM Potency
TKC022818 P08659 Luciferin 4-monooxygenase 26855 nM Potency
TKC022818 Q6W5P4 Neuropeptide S receptor NPSR1 25119 nM Potency
TKC022818 B2RXH2 Lysine-specific demethylase 4E KDM4E 35481 nM Potency
TKC022818 P02791 Ferritin light chain FTL 17783 nM Potency
TKC022818 Q92830 Histone acetyltransferase KAT2A KAT2A 126 nM Potency
TKC022818 P10520 Streptokinase A ska 7080 nM EC50
TKC022818 P51450 Nuclear receptor ROR-gamma Rorc 5623 nM Potency
TKC022818 Q194T2 Non-structural protein 1 NS1 19953 nM Potency
TKC022818 P17861 X-box-binding protein 1 XBP1 10000 nM IC50
TKC022818 P35639 DNA damage-inducible transcript 3 protein Ddit3 >9520 nM IC50
TKC022818 P35639 DNA damage-inducible transcript 3 protein Ddit3 >10000 nM IC50
TKC022818 Q14974 Importin subunit beta-1 KPNB1 89125 nM Potency
TKC022818 P10253 Lysosomal alpha-glucosidase GAA 28184 nM Potency
TKC022818 P80244 ATP-dependent Clp protease proteolytic subunit clpP 31623 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P10636 TAU_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P10636 TAU_HUMAN Alzheimer disease [ICD-11: 8A20]
P10636 TAU_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P10636 TAU_HUMAN Choreiform disorder [ICD-11: 8A01]
P10636 TAU_HUMAN Parkinsonism [ICD-11: 8A00]
P10636 TAU_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P10636 TAU_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
P43220 GLP1R_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P43220 GLP1R_HUMAN Obesity [ICD-11: 5B80-5B81]
P43220 GLP1R_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P43220 GLP1R_HUMAN Type-1/2 diabete [ICD-11: 5A10-5A11]
P43220 GLP1R_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P43220 GLP1R_HUMAN Diabetes mellitus [ICD-11: 5A10]
P43220 GLP1R_HUMAN Dyspepsia [ICD-11: MD92]
P43220 GLP1R_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P43220 GLP1R_HUMAN Intracranial injury [ICD-11: NA07]
P43220 GLP1R_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
P37840 SYUA_HUMAN Parkinsonism [ICD-11: 8A00]
P37840 SYUA_HUMAN Alzheimer disease [ICD-11: 8A20]
P37840 SYUA_HUMAN Autonomic nervous system disorder [ICD-11: 8D87]
Q13526 PIN1_HUMAN Lung cancer [ICD-11: 2C25]
Q13526 PIN1_HUMAN Nasopharyngeal cancer [ICD-11: 2B6B]
P10253 LYAG_HUMAN Inborn carbohydrate metabolism error [ICD-11: 5C51]