Basic Information

Terpenoid ID TKC022814
Cell line 0
Protein target 17
DiseaseNCIT 0
ORDO 0
ICD 34

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC022814 HepG2 22387.0 nM Potency C3728 Orphanet_449

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC022814 P10636 Microtubule-associated protein tau MAPT 891 nM Potency
TKC022814 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 11582 nM Potency
TKC022814 P43220 Glucagon-like peptide 1 receptor GLP1R 28184 nM Potency
TKC022814 P84022 Mothers against decapentaplegic homolog 3 SMAD3 22387 nM Potency
TKC022814 Q03431 Parathyroid hormone/parathyroid hormone-related peptide receptor PTH1R 19953 nM Potency
TKC022814 Q77YF9 Protein Vpr vpr 31623 nM Potency
TKC022814 Q99700 Ataxin-2 ATXN2 33588 nM Potency
TKC022814 O75496 Geminin GMNN 12995 nM Potency
TKC022814 P37840 Alpha-synuclein SNCA 35481 nM Potency
TKC022814 Q13148 TAR DNA-binding protein 43 TARDBP 35481 nM Potency
TKC022814 P28482 Mitogen-activated protein kinase 1 MAPK1 28184 nM Potency
TKC022814 P83916 Chromobox protein homolog 1 CBX1 100000 nM Potency
TKC022814 P02791 Ferritin light chain FTL 12589 nM Potency
TKC022814 Q03164 Histone-lysine N-methyltransferase 2A KMT2A 31623 nM Potency
TKC022814 P51450 Nuclear receptor ROR-gamma Rorc 12589 nM Potency
TKC022814 Q194T2 Non-structural protein 1 NS1 12589 nM Potency
TKC022814 Q63470 Dual specificity tyrosine-phosphorylation-regulated kinase 1A Dyrk1a 10097 nM AC50
TKC022814 Q8IL88 HSP40, subfamily A PF3D7_1437900 4 uM AbsAC1000_uM

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P10636 TAU_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P10636 TAU_HUMAN Alzheimer disease [ICD-11: 8A20]
P10636 TAU_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P10636 TAU_HUMAN Choreiform disorder [ICD-11: 8A01]
P10636 TAU_HUMAN Parkinsonism [ICD-11: 8A00]
P10636 TAU_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P10636 TAU_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
P43220 GLP1R_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P43220 GLP1R_HUMAN Obesity [ICD-11: 5B80-5B81]
P43220 GLP1R_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P43220 GLP1R_HUMAN Type-1/2 diabete [ICD-11: 5A10-5A11]
P43220 GLP1R_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P43220 GLP1R_HUMAN Diabetes mellitus [ICD-11: 5A10]
P43220 GLP1R_HUMAN Dyspepsia [ICD-11: MD92]
P43220 GLP1R_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P43220 GLP1R_HUMAN Intracranial injury [ICD-11: NA07]
P43220 GLP1R_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q03431 PTH1R_HUMAN Low bone mass disorder [ICD-11: FB83]
Q03431 PTH1R_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
P37840 SYUA_HUMAN Parkinsonism [ICD-11: 8A00]
P37840 SYUA_HUMAN Alzheimer disease [ICD-11: 8A20]
P37840 SYUA_HUMAN Autonomic nervous system disorder [ICD-11: 8D87]
Q13148 TADBP_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
Q13148 TADBP_HUMAN Alzheimer disease [ICD-11: 8A20]
P28482 MK01_HUMAN Melanoma [ICD-11: 2C30]
P28482 MK01_HUMAN Pancreatic cancer [ICD-11: 2C10]
P28482 MK01_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P28482 MK01_HUMAN Arteries/arterioles disorder [ICD-11: BD52]
P28482 MK01_HUMAN Allergic/hypersensitivity disorder [ICD-11: 4A80-4A8Z]
P28482 MK01_HUMAN Transplant rejection [ICD-11: NE84]
P28482 MK01_HUMAN Mature T-cell lymphoma [ICD-11: 2A90]
P28482 MK01_HUMAN Rheumatoid arthritis [ICD-11: FA20]