Basic Information

Terpenoid ID TKC019353
Cell line 0
Protein target 6
DiseaseNCIT 0
ORDO 0
ICD 12

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC019353 Lymphoblastoid cells 79433.0 nM Potency
TKC019353 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 60.0 % GI C27677
TKC019353 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 11000.0 nM IC50 C27677
TKC019353 U-937 U937; U 937 3000.0 nM IC50 C8263 Orphanet_514
TKC019353 HepG2 290000.0 nM IC50 C3728 Orphanet_449
TKC019353 SW-620 SW-620; SW 620; SW.620 222000.0 nM IC50 C4349
TKC019353 T47D 224000.0 nM IC50 C4194

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC019353 O42275 Acetylcholinesterase ache 300000 nM Ki
TKC019353 P0DTD1 Replicase polyprotein 1ab rep 11 % Inhibition
TKC019353 P83916 Chromobox protein homolog 1 CBX1 89125 nM Potency
TKC019353 P00811 Beta-lactamase ampC 22387 nM Potency
TKC019353 P10828 Thyroid hormone receptor beta THRB 4467 nM Potency
TKC019353 Q8MK44 Diacylglycerol O-acyltransferase 1 DGAT1 28 % Inhibition
TKC019353 Q9BGL2 Lecithin retinol acyltransferase LRAT 0 % Inhibition
TKC019353 P0DTE4 UDP-glucuronosyltransferase 2A1 UGT2A1 278 pm/min/mg Activity
TKC019353 P22309 UDP-glucuronosyltransferase 1A1 UGT1A1 0 pm/min/mg Activity
TKC019353 P22310 UDP-glucuronosyltransferase 1A4 UGT1A4 0 pm/min/mg Activity
TKC019353 P46098 5-hydroxytryptamine receptor 3A HTR3A 141254 nM IC50
TKC019353 Q14974 Importin subunit beta-1 KPNB1 125893 nM Potency
TKC019353 Q75NA5 Gamma-aminobutyric acid receptor subunit beta Rdl 124 % Activity

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P10828 THB_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
P10828 THB_HUMAN Hypo-thyroidism [ICD-11: 5A00]
P10828 THB_HUMAN Inborn lipid metabolism error [ICD-11: 5C52]
P10828 THB_HUMAN Skin postprocedural disorder [ICD-11: EL8Y]
P10828 THB_HUMAN Thyrotoxicosis [ICD-11: 5A02]
P22309 UD11_HUMAN Inborn porphyrin/heme metabolism error [ICD-11: 5C58]
P46098 5HT3A_HUMAN Chronic pain [ICD-11: MG30]
P46098 5HT3A_HUMAN Corneal disease [ICD-11: 9A76-9A78]
P46098 5HT3A_HUMAN Epilepsy/seizure [ICD-11: 8A61-8A6Z]
P46098 5HT3A_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P46098 5HT3A_HUMAN Nausea/vomiting [ICD-11: MD90]
P46098 5HT3A_HUMAN Gastro-oesophageal reflux disease [ICD-11: DA22]
P46098 5HT3A_HUMAN Schizophrenia [ICD-11: 6A20]