Basic Information

Terpenoid ID TKC015409
Chirality TKC101017
Cell line 0
Protein target 6
DiseaseNCIT 0
ORDO 0
ICD 7

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC015409 Panel NCI-60 (60 carcinoma cell lines) 7000.0 nM GI50
TKC015409 COLO 205 Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 1900.0 nM GI50 C4349
TKC015409 C3H 10T1/2 C3H/10T1/2-clone8; C3H/10T1/2 CL8; C3H10T1/2 clone8; C3H10T1/2CL8; 10T1/2(clone8); 10T1/2; C3H10T1-2; C3H10T1/2; C3H-10T1/2; C3H 10T1/2; C3H/10T1/2 1100.0 nM Effective concentration
TKC015409 KB KB (HeLa derivative); HeLa-KB; Strain KB 1000.0 ug.mL-1 IC50 C27677
TKC015409 Vero VERO; VeroCCL81; Vero 81; Vero-81; Verda reno 79000.0 nM CC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC015409 O42275 Acetylcholinesterase ache -10 % Inhibition
TKC015409 P17252 Protein kinase C alpha type PRKCA 4.83 nM Ki
TKC015409 P81908 Cholinesterase BCHE 4 % Inhibition
TKC015409 O94806 Serine/threonine-protein kinase D3 PRKD3 190 nM Ki
TKC015409 O94806 Serine/threonine-protein kinase D3 PRKD3 910 nM EC50
TKC015409 Q05655 Protein kinase C delta type PRKCD 24.6 nM Ki
TKC015409 P04409 Protein kinase C alpha type PRKCA 5 nM Ki
TKC015409 Q01279 Epidermal growth factor receptor Egfr 220 nM Effective concentration
TKC015409 P98161 Polycystin-1 PKD1 12.9 nM Ki

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P17252 KPCA_HUMAN Lung cancer [ICD-11: 2C25]
P17252 KPCA_HUMAN Muscular atrophy [ICD-11: 8B61]
P17252 KPCA_HUMAN Transplant rejection [ICD-11: NE84]
P17252 KPCA_HUMAN Nephritic syndrome [ICD-11: GB40]
P17252 KPCA_HUMAN Human immunodeficiency virus disease [ICD-11: 1C60-1C62]
Q05655 KPCD_HUMAN Myocardial infarction [ICD-11: BA41-BA43]
Q05655 KPCD_HUMAN Human immunodeficiency virus disease [ICD-11: 1C60-1C62]
Q05655 KPCD_HUMAN Human immunodeficiency virus disease [ICD-11: 1C60-1C62]