Basic Information

Terpenoid ID TKC014800
Chirality TKC107873
Cell line 0
Protein target 14
DiseaseNCIT 0
ORDO 0
ICD 14

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC014800 A549 19000.0 nM IC50 C3512
TKC014800 A2780 A-2780; 2780; A2780S; A2780par 1500.0 nM IC50 C7979 Orphanet_454723
TKC014800 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 50.0 nM IC50 C27677

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC014800 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 581 nM Potency
TKC014800 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 2593 nM Potency
TKC014800 P43220 Glucagon-like peptide 1 receptor GLP1R 3548 nM Potency
TKC014800 Q99700 Ataxin-2 ATXN2 7519 nM Potency
TKC014800 O75496 Geminin GMNN 461 nM Potency
TKC014800 P01215 Glycoprotein hormones alpha chain CGA 2818 nM Potency
TKC014800 Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G APOBEC3G 1122 nM Potency
TKC014800 P00811 Beta-lactamase ampC 63096 nM Potency
TKC014800 P63096 Guanine nucleotide-binding protein G GNAI1 1778 nM Potency
TKC014800 P02791 Ferritin light chain FTL 28184 nM Potency
TKC014800 Q03164 Histone-lysine N-methyltransferase 2A KMT2A 3548 nM Potency
TKC014800 Q9Y468 Lethal(3)malignant brain tumor-like protein 1 L3MBTL1 44668 nM Potency
TKC014800 O15118 NPC intracellular cholesterol transporter 1 NPC1 1259 nM Potency
TKC014800 Q194T2 Non-structural protein 1 NS1 7080 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Liver cancer [ICD-11: 2C12]
O75874 IDHC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P43220 GLP1R_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P43220 GLP1R_HUMAN Obesity [ICD-11: 5B80-5B81]
P43220 GLP1R_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P43220 GLP1R_HUMAN Type-1/2 diabete [ICD-11: 5A10-5A11]
P43220 GLP1R_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P43220 GLP1R_HUMAN Diabetes mellitus [ICD-11: 5A10]
P43220 GLP1R_HUMAN Dyspepsia [ICD-11: MD92]
P43220 GLP1R_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P43220 GLP1R_HUMAN Intracranial injury [ICD-11: NA07]
P43220 GLP1R_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]