Basic Information

Terpenoid ID TKC014745
Cell line 1
Protein target 1
DiseaseNCIT 1
ORDO 1
ICD 6

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC014745 WI-38 VA13 WI 38 VA13 subline 2RA; WI 38 VA-13 subline 2RA; WI 38VA13 subline 2RA; WI-38 VA13 sub 2 RA; WI38-VA13 subline 2RA; WI38 VA13/2RA; WI38VA13/2RA; VA13 2RA; WI-38 VA13; WI 38 VA 13; WI38-VA13; WI38/VA13; WI38VA13; VA-13; VA13; AG07217; AG7217 53100.0 nM IC50
TKC014745 HepG2 18500.0 nM IC50 C3728 Orphanet_449

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC014745 P08183 ATP-dependent translocase ABCB1 ABCB1 127 % Activity

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P08183 MDR1_HUMAN Lung cancer [ICD-11: 2C25]
P08183 MDR1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08183 MDR1_HUMAN Bacterial infection [ICD-11: 1A00-1C4Z]
P08183 MDR1_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P08183 MDR1_HUMAN Adrenal cancer [ICD-11: 2D11]
P08183 MDR1_HUMAN Ovarian cancer [ICD-11: 2C73]