Basic Information

Terpenoid ID TKC014471
Cell line 60
Protein target 1
DiseaseNCIT 62
ORDO 21
ICD 0

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC014471 MDA-N MDAN 177.0 nM GI50 C3802
TKC014471 SN12C SN-12C 156.0 nM GI50 C9385 Orphanet_217071
TKC014471 ACHN 114.0 nM GI50 C6975 Orphanet_319298
TKC014471 NCI-H23 NCI.H23; NCI H23; H-23; H23; NCIH23 209.0 nM GI50 C3512
TKC014471 HOP-92 HOP 92; HOP.92; HOP92; Hop92; Hopkins-92 210.0 nM GI50 C2926
TKC014471 UO-31 UO.31; UO31; U031 241.0 nM GI50 C9385 Orphanet_217071
TKC014471 DU-145 DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 716.0 nM GI50 C4863
TKC014471 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 18.0 nM GI50 C9154 Orphanet_519
TKC014471 SK-MEL-5 SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel 267.0 nM GI50 C3510
TKC014471 SF-539 SF-539; SF-539 BT; SF.539; SF 539 177.0 nM GI50 C3796 Orphanet_251576
TKC014471 K562 K562; K.562; K 562; KO; GM05372; GM05372E 87.0 nM GI50 C9110 Orphanet_521
TKC014471 Malme-3M MALME-3M; MALME 3M; Malme-3 M; MALME.3M; Malme3M; MALME3M; Malme-3 Monolayer 177.0 nM GI50 C3224
TKC014471 A498 A498 305.0 nM GI50 C9385 Orphanet_217071
TKC014471 OVCAR-3 Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 139.0 nM GI50 C105555
TKC014471 MOLT-4 Molt-4; MOLT 4; Molt 4; MOLT.4; MOLT4; Molt4; GM02219; GM02219C; GM2219C; GM02219D 91.0 nM GI50 C9142 Orphanet_99861
TKC014471 NCI/ADR-RES NCI/ADR-RES; NCI.ADR.RES; NCIADR.RES; NCI/ADRRES; NCIADRRES; ADR-RES; MCF-7/ADR; MCF-7/ADR-RES; MCF-7/AdrR; MCF-7/Adr; MCF-7/adr; MCF-7ADR; MCF7-ADR; MCF7ADR; OVCAR-8/ADR; OVCAR8/ADR 189.0 nM GI50 C105555
TKC014471 HOP-62 HOP 62; Hop 62; HOP.62; HOP62; Hop62; Hopkins-62 575.0 nM GI50 C3512
TKC014471 OVCAR-8 OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 130.0 nM GI50 C105555
TKC014471 U-251 U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) 175.0 nM GI50 C60781 Orphanet_94
TKC014471 SNB-19 SNB.19; SNB19; Surgical Neurology Branch-19 692.0 nM GI50 C60781 Orphanet_94
TKC014471 OVCAR-5 OVCAR 5; NIH:OVCAR-5; OVCAR.5; OVCAR5; Ovcar5; OVCA5 303.0 nM GI50 C105555
TKC014471 MDA-MB-231 MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 184.0 nM GI50 C5214
TKC014471 TK-10 TK.10; TK 10; TK10 229.0 nM GI50 C4033 Orphanet_319276
TKC014471 SR SR-786; SR786 146.0 nM GI50 C37193 Orphanet_300895
TKC014471 NCI-H522 NCI.H522; H522; H-522; NCI-522; NCI522; NCIH522 80.0 nM GI50 C3512
TKC014471 SW-620 SW-620; SW 620; SW.620 50.0 nM GI50 C4349
TKC014471 KM12 KM-12; KM.12 404.0 nM GI50 C4910
TKC014471 M14 M14-MEL; UCLA-SO-M14; UCLA SO M14; UCLA-SO-14; UCLASO-M14; Melanoma 14; M-14 262.0 nM GI50 C3802
TKC014471 NCI-H322M NCI.H322M; H322M; H-322M; H-322m 975.0 nM GI50 C2923
TKC014471 RPMI-8226 RPMI 8226; RPMI.8226; RPMI8226; RPMI no. 8226; RPMI no 8226; RPMI #8226; 8226; RPMI 8226/S; RPMI-8226S; RPMI8226/S; 8226/S; Roswell Park Memorial Institute 8226; GM02132; GM2132; GM 2132; GM02132C; Simpson 59.0 nM GI50 C3242 Orphanet_29073
TKC014471 OVCAR-4 OVCAR 4; NIH:OVCAR-4; NIH:OVCAR4; OVCAR.4; OVCAR4; Ovcar4 241.0 nM GI50 C105555
TKC014471 LOX IMVI LOX/IMVI; LOX IMVI; LOXIM-VI; LOXIMVI; LOX 277.0 nM GI50 C3802
TKC014471 BT-549 BT 549; BT.549; BT549 120.0 nM GI50 C4194
TKC014471 SK-MEL-2 SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 230.0 nM GI50 C3224
TKC014471 HCC 2998 HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 519.0 nM GI50 C4349
TKC014471 A549 805.0 nM GI50 C3512
TKC014471 SNB-75 SNB.75; SNB75; Surgical Neurology Branch-75 74.0 nM GI50 C3058 Orphanet_360
TKC014471 HCT-15 HCT-15; HCT.15; HCT15 200.0 nM GI50 C4349
TKC014471 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 76.0 nM GI50 C4910
TKC014471 EKVX 359.0 nM GI50 C3512
TKC014471 SF-268 SF-268; SF.268; SF 268 240.0 nM GI50 C60781 Orphanet_94
TKC014471 PC-3 PC3; PC.3 97.0 nM GI50 C4863
TKC014471 MCF7 217.0 nM GI50 C4194
TKC014471 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 3741.0 nM GI50 C7978
TKC014471 NCI-H460 NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 255.0 nM GI50 C4450
TKC014471 T47D 89.0 nM GI50 C4194
TKC014471 UACC-62 UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 515.0 nM GI50 C3224
TKC014471 CAKI-1 CAL 1; Centre Antoine Lacassagne-1 200.0 nM GI50 C3224
TKC014471 SF-295 SF-295; SF.295; SF 295 586.0 nM GI50 C3058 Orphanet_360
TKC014471 MDA-MB-435 MDA-MB435; MDAMB435; MDA.MB.435; MDA-435; MDA 435; MDA435; MD Anderson-Metastatic Breast-435 174.0 nM GI50 C3802
TKC014471 IGROV-1 Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P 219.0 nM GI50 C7979 Orphanet_454723
TKC014471 Hs-578T HS 578T; Hs-578T; HS-578T; Hs_578t; Hs-578-T; HS-578-T; Hs 578.T; HS578T; Hs578T; Hs578t; HS0578T; 578T; HS578; Hs578; Homo sapiens No. 578, tumor cells 221.0 nM GI50 C4194
TKC014471 786-0 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT 112.0 nM GI50 C9385 Orphanet_217071
TKC014471 UACC-257 UACC 257; UACC.257; UACC257; University of Arizona Cell Culture-257 219.0 nM GI50 C3224
TKC014471 CCRF-CEM CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C 27.0 nM GI50 C7953 Orphanet_99861
TKC014471 HT-29 HT 29; HT29 92.0 nM GI50 C4349
TKC014471 NCI-H226 NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226 378.0 nM GI50 C45662 Orphanet_50251
TKC014471 SK-MEL-28 SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 234.0 nM GI50 C3510
TKC014471 RXF 393 RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL 106.0 nM GI50 C9385 Orphanet_217071
TKC014471 COLO 205 Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 77.0 nM GI50 C4349

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC014471 O15264 Mitogen-activated protein kinase 13 MAPK13 25 % Inhibition

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11