Basic Information

Terpenoid ID TKC013738
Chirality TKC092268
Cell line 0
Protein target 7
DiseaseNCIT 0
ORDO 0
ICD 32

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC013738 A549 1.0 ug ml-1 ED50 C3512
TKC013738 MCF7 4.0 ug ml-1 ED50 C4194
TKC013738 HT-29 HT 29; HT29 3.0 ug ml-1 ED50 C4349
TKC013738 A498 A498 1.0 ug ml-1 ED50 C9385 Orphanet_217071
TKC013738 PC-3 PC3; PC.3 3.0 ug ml-1 ED50 C4863
TKC013738 MIA PaCa-2 MIA-PaCa-2; MIA-PACA-2; MIA-Pa-Ca-2; MIA Paca2; MIA PaCa2; MiaPaCa-2; MIAPACA-2; MiaPaca.2; MiaPaCa2; Miapaca2; MIAPaCa2; MIAPACA2; Mia PACA 2; MIAPaCa-2; PaCa2; MiaPaCa 2.0 ug ml-1 ED50 C9120

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC013738 P10636 Microtubule-associated protein tau MAPT 15849 nM Potency
TKC013738 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 EHMT2 14125 nM Potency
TKC013738 P25779 Cruzipain 14125 nM Potency
TKC013738 P11021 Endoplasmic reticulum chaperone BiP HSPA5 25119 nM Potency
TKC013738 P51450 Nuclear receptor ROR-gamma Rorc 19953 nM Potency
TKC013738 O35433 Transient receptor potential cation channel subfamily V member 1 Trpv1 0.13 nM Ki
TKC013738 O35433 Transient receptor potential cation channel subfamily V member 1 Trpv1 180 nM IC50
TKC013738 Q8NER1 Transient receptor potential cation channel subfamily V member 1 TRPV1 24 nM Ki
TKC013738 Q8NER1 Transient receptor potential cation channel subfamily V member 1 TRPV1 23 nM Ki
TKC013738 Q8NER1 Transient receptor potential cation channel subfamily V member 1 TRPV1 14 nM Ki

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P10636 TAU_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P10636 TAU_HUMAN Alzheimer disease [ICD-11: 8A20]
P10636 TAU_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P10636 TAU_HUMAN Choreiform disorder [ICD-11: 8A01]
P10636 TAU_HUMAN Parkinsonism [ICD-11: 8A00]
P10636 TAU_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P10636 TAU_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
Q96KQ7 EHMT2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96KQ7 EHMT2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q96KQ7 EHMT2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P25779 CYSP_TRYCR Parasitic worm infestation [ICD-11: 1F90]
P25779 CYSP_TRYCR Malaria [ICD-11: 1F40-1F45]
P11021 BIP_HUMAN Melanoma [ICD-11: 2C30]
P11021 BIP_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q8NER1 TRPV1_HUMAN Visual system disease [ICD-11: 9E1Z]
Q8NER1 TRPV1_HUMAN General pain disorder [ICD-11: 8E43]
Q8NER1 TRPV1_HUMAN Knee osteoarthritis [ICD-11: FA01]
Q8NER1 TRPV1_HUMAN Lower limb mononeuropathy [ICD-11: 8C11]
Q8NER1 TRPV1_HUMAN Pain [ICD-11: MG30-MG3Z]
Q8NER1 TRPV1_HUMAN Atopic eczema [ICD-11: EA80]
Q8NER1 TRPV1_HUMAN Chronic pain [ICD-11: MG30]
Q8NER1 TRPV1_HUMAN Functional bladder disorder [ICD-11: GC50]
Q8NER1 TRPV1_HUMAN Migraine [ICD-11: 8A80]
Q8NER1 TRPV1_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
Q8NER1 TRPV1_HUMAN Rheumatoid arthritis [ICD-11: FA20]
Q8NER1 TRPV1_HUMAN Asthma [ICD-11: CA23]
Q8NER1 TRPV1_HUMAN Acute/chronic pain [ICD-11: MG30-MG31]
Q8NER1 TRPV1_HUMAN Esophagus sensitivity [ICD-11: DA2Y-DA2Z]
Q8NER1 TRPV1_HUMAN Gastro-oesophageal reflux disease [ICD-11: DA22]
Q8NER1 TRPV1_HUMAN Neuropathy [ICD-11: 8C0Z]
Q8NER1 TRPV1_HUMAN Zoster [ICD-11: 1E91]
Q8NER1 TRPV1_HUMAN Cough [ICD-11: MD12]
Q8NER1 TRPV1_HUMAN Visual system disease [ICD-11: 9E1Z]
Q8NER1 TRPV1_HUMAN General pain disorder [ICD-11: 8E43]
Q8NER1 TRPV1_HUMAN Knee osteoarthritis [ICD-11: FA01]
Q8NER1 TRPV1_HUMAN Lower limb mononeuropathy [ICD-11: 8C11]
Q8NER1 TRPV1_HUMAN Pain [ICD-11: MG30-MG3Z]
Q8NER1 TRPV1_HUMAN Atopic eczema [ICD-11: EA80]
Q8NER1 TRPV1_HUMAN Chronic pain [ICD-11: MG30]
Q8NER1 TRPV1_HUMAN Functional bladder disorder [ICD-11: GC50]
Q8NER1 TRPV1_HUMAN Migraine [ICD-11: 8A80]
Q8NER1 TRPV1_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
Q8NER1 TRPV1_HUMAN Rheumatoid arthritis [ICD-11: FA20]
Q8NER1 TRPV1_HUMAN Asthma [ICD-11: CA23]
Q8NER1 TRPV1_HUMAN Acute/chronic pain [ICD-11: MG30-MG31]
Q8NER1 TRPV1_HUMAN Esophagus sensitivity [ICD-11: DA2Y-DA2Z]
Q8NER1 TRPV1_HUMAN Gastro-oesophageal reflux disease [ICD-11: DA22]
Q8NER1 TRPV1_HUMAN Neuropathy [ICD-11: 8C0Z]
Q8NER1 TRPV1_HUMAN Zoster [ICD-11: 1E91]
Q8NER1 TRPV1_HUMAN Cough [ICD-11: MD12]
Q8NER1 TRPV1_HUMAN Visual system disease [ICD-11: 9E1Z]
Q8NER1 TRPV1_HUMAN General pain disorder [ICD-11: 8E43]
Q8NER1 TRPV1_HUMAN Knee osteoarthritis [ICD-11: FA01]
Q8NER1 TRPV1_HUMAN Lower limb mononeuropathy [ICD-11: 8C11]
Q8NER1 TRPV1_HUMAN Pain [ICD-11: MG30-MG3Z]
Q8NER1 TRPV1_HUMAN Atopic eczema [ICD-11: EA80]
Q8NER1 TRPV1_HUMAN Chronic pain [ICD-11: MG30]
Q8NER1 TRPV1_HUMAN Functional bladder disorder [ICD-11: GC50]
Q8NER1 TRPV1_HUMAN Migraine [ICD-11: 8A80]
Q8NER1 TRPV1_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
Q8NER1 TRPV1_HUMAN Rheumatoid arthritis [ICD-11: FA20]
Q8NER1 TRPV1_HUMAN Asthma [ICD-11: CA23]
Q8NER1 TRPV1_HUMAN Acute/chronic pain [ICD-11: MG30-MG31]
Q8NER1 TRPV1_HUMAN Esophagus sensitivity [ICD-11: DA2Y-DA2Z]
Q8NER1 TRPV1_HUMAN Gastro-oesophageal reflux disease [ICD-11: DA22]
Q8NER1 TRPV1_HUMAN Neuropathy [ICD-11: 8C0Z]
Q8NER1 TRPV1_HUMAN Zoster [ICD-11: 1E91]
Q8NER1 TRPV1_HUMAN Cough [ICD-11: MD12]