Basic Information

Terpenoid ID TKC012725
Chirality TKC101269
Cell line 7
Protein target 1
DiseaseNCIT 8
ORDO 4
ICD 9

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC012725 K562 K562; K.562; K 562; KO; GM05372; GM05372E 16080.0 nM IC50 C9110 Orphanet_521
TKC012725 U-937 U937; U 937 11790.0 nM IC50 C8263 Orphanet_514
TKC012725 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 26810.0 nM IC50 C9154 Orphanet_519
TKC012725 HT-1080 Ht-1080; HT 1080; HT1080; HT 1080.T 2020.0 nM IC50 C3043 Orphanet_2030
TKC012725 A549 13110.0 nM IC50 C3512
TKC012725 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 22960.0 nM IC50 C4910
TKC012725 HepG2 8040.0 nM IC50 C3728 Orphanet_449
TKC012725 MCF7 2390.0 nM IC50 C4194
TKC012725 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 5560.0 nM IC50 C27677

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC012725 Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH2 51 % Inhibition

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q12809 KCNH2_HUMAN Heart failure [ICD-11: BD10-BD1Z]
Q12809 KCNH2_HUMAN Sleep-wake disorder [ICD-11: 7A00-7B2Z]
Q12809 KCNH2_HUMAN Malaria [ICD-11: 1F40-1F45]
Q12809 KCNH2_HUMAN Multiple sclerosis [ICD-11: 8A40]
Q12809 KCNH2_HUMAN Pain [ICD-11: MG30-MG3Z]
Q12809 KCNH2_HUMAN Cardiac arrhythmia [ICD-11: BC9Z]
Q12809 KCNH2_HUMAN Angina pectoris [ICD-11: BA40]
Q12809 KCNH2_HUMAN Genetic cardiac arrhythmia [ICD-11: BC65]
Q12809 KCNH2_HUMAN Ovarian cancer [ICD-11: 2C73]