Basic Information

Terpenoid ID TKC012116
Cell line 0
Protein target 20
DiseaseNCIT 0
ORDO 0
ICD 34

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC012116 Vero VERO; VeroCCL81; Vero 81; Vero-81; Verda reno 30480.0 nM IC50
TKC012116 HEK293 6513.0 nM Potency

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC012116 Q16637 Survival motor neuron protein SMN1,SMN2 7080 nM Potency
TKC012116 Q16637 Survival motor neuron protein SMN1,SMN2 7080 nM Potency
TKC012116 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 1836 nM Potency
TKC012116 Q00653 Nuclear factor NF-kappa-B p100 subunit NFKB2 4450 nM EC50
TKC012116 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 7308 nM Potency
TKC012116 P43220 Glucagon-like peptide 1 receptor GLP1R 7080 nM Potency
TKC012116 P84022 Mothers against decapentaplegic homolog 3 SMAD3 2909 nM Potency
TKC012116 Q16236 Nuclear factor erythroid 2-related factor 2 NFE2L2 18356 nM Potency
TKC012116 Q99700 Ataxin-2 ATXN2 10000 nM Potency
TKC012116 Q04206 Transcription factor p65 RELA 4450 nM EC50
TKC012116 O75496 Geminin GMNN 1032 nM Potency
TKC012116 P00811 Beta-lactamase ampC 316 nM Potency
TKC012116 Q96QE3 ATPase family AAA domain-containing protein 5 ATAD5 2060 nM Potency
TKC012116 Q9NR56 Muscleblind-like protein 1 MBNL1 100000 nM Potency
TKC012116 Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B BAZ2B 708 nM Potency
TKC012116 Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F APOBEC3F 2512 nM Potency
TKC012116 P02545 Prelamin-A/C LMNA 15849 nM Potency
TKC012116 P42858 Huntingtin HTT 35481 nM Potency
TKC012116 O15118 NPC intracellular cholesterol transporter 1 NPC1 2818 nM Potency
TKC012116 O75030 Microphthalmia-associated transcription factor MITF 1628 nM AC50
TKC012116 P51151 Ras-related protein Rab-9A RAB9A 2818 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
Q00653 NFKB2_HUMAN Ulcerative colitis [ICD-11: DD71]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Liver cancer [ICD-11: 2C12]
O75874 IDHC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P43220 GLP1R_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P43220 GLP1R_HUMAN Obesity [ICD-11: 5B80-5B81]
P43220 GLP1R_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P43220 GLP1R_HUMAN Type-1/2 diabete [ICD-11: 5A10-5A11]
P43220 GLP1R_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P43220 GLP1R_HUMAN Diabetes mellitus [ICD-11: 5A10]
P43220 GLP1R_HUMAN Dyspepsia [ICD-11: MD92]
P43220 GLP1R_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P43220 GLP1R_HUMAN Intracranial injury [ICD-11: NA07]
P43220 GLP1R_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q16236 NF2L2_HUMAN Ataxic disorder [ICD-11: 8A03]
Q16236 NF2L2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q16236 NF2L2_HUMAN Glaucoma [ICD-11: 9C61]
Q16236 NF2L2_HUMAN Lung cancer [ICD-11: 2C25]
Q16236 NF2L2_HUMAN Macular degeneration [ICD-11: 9B75]
Q16236 NF2L2_HUMAN Melanoma [ICD-11: 2C30]
Q16236 NF2L2_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
Q16236 NF2L2_HUMAN Pulmonary hypertension [ICD-11: BB01]
Q16236 NF2L2_HUMAN Subarachnoid haemorrhage [ICD-11: 8B01]
Q16236 NF2L2_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
Q16236 NF2L2_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q16236 NF2L2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q16236 NF2L2_HUMAN Motor neuron disease [ICD-11: 8B60]
Q16236 NF2L2_HUMAN Multiple sclerosis [ICD-11: 8A40]
P42858 HD_HUMAN Choreiform disorder [ICD-11: 8A01]
P51151 RAB9A_HUMAN Fungal infection [ICD-11: 1F29-1F2F]