Basic Information

Terpenoid ID TKC001231
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 13

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC001231 A2780 A-2780; 2780; A2780S; A2780par 5400.0 nM GI50 C7979 Orphanet_454723
TKC001231 SW1573 SW-1573; SW 1573 22000.0 nM GI50 C2923
TKC001231 WiDr WiDR; WIDR; WiDr/S; WiDr-TC; WiDrTC; LED-WiDr; Led-WiDr 32000.0 nM GI50 C4349
TKC001231 T47D 32000.0 nM GI50 C4194
TKC001231 HBL-100 HBL 100; HBL100 4600.0 nM GI50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC001231 P14324 Farnesyl pyrophosphate synthase FDPS 18700 nM IC50
TKC001231 O95749 Geranylgeranyl pyrophosphate synthase GGPS1 >100000 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P14324 FPPS_HUMAN Bone paget disease [ICD-11: FB85]
P14324 FPPS_HUMAN Focal/segmental autonomic disorder [ICD-11: 8D8A]
P14324 FPPS_HUMAN Low bone mass disorder [ICD-11: FB83]
P14324 FPPS_HUMAN Mineral excesses [ICD-11: 5B91]
P14324 FPPS_HUMAN Musculoskeletal system/connective tissue disease [ICD-11: FC0Z]
P14324 FPPS_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P14324 FPPS_HUMAN Colorectal cancer [ICD-11: 2B91]
P14324 FPPS_HUMAN Mature T-cell lymphoma [ICD-11: 2A90]
P14324 FPPS_HUMAN Myelodysplastic syndrome [ICD-11: 2A37]
P14324 FPPS_HUMAN Myeloproliferative neoplasm [ICD-11: 2A20]
P14324 FPPS_HUMAN Pancreatic cancer [ICD-11: 2C10]
P14324 FPPS_HUMAN Sexually transmitted infection [ICD-11: 1A9Y-1A9Z]
P14324 FPPS_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]